Danish actor Jesper Christensen told TV2 (via MI6) that Mr. White, the boss of Le Chiffre in Casino Royale, will return in Bond 22.
(Spoiler ahead!) The actor said that his character would endure 007’s interrogation methods at the beginning of the film. So, as Paul Haggis said, the movie literally picks up 2 minutes later.
The 22nd installment starts filming in December for a November 7, 2008 release.